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*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]*Join the Physionic Insiders: https://bit.ly/PhysionicInsiders2 *HEALTH AUTONOMY [COURSE]*Learn to Analyze & Apply Studies for Yourself: https://bit.ly/healthautonomy*JOIN THE COMMUNITY*Join my Community [It’s Free!]: https://bit.ly/PhysionicCommunity2*EMAIL LIST*1-2 Weekly Email of Value [It’s Free!]: http://bit.ly/2AXIzK6*HIRE ME FOR CONSULTING:* Consulting: https://bit.ly/3dmUl2H Created with Biorender0:00 - Introduction1:14 - A Solid 13 Studies, Right?5:14 - A Failed Study holds a Clue7:40 - Berberine on Plaque Reversing, Revisited11:17 - Ever had these effects with Berberine?References**Full Funding/Conflicts are provided in the free article (found in email list and Physionic Community Article Library)[1] Zhu F, Chen L, Zhu J. Effects of berberine combined with atorvastatin on serum high-sensitivity C-reactive protein and adipocyte fatty acid-binding protein levels in patients with acute ischemic stroke. Chinese Journal of Contemporary Neurology and Neurosurgery. 2015;15(1). doi:10.3969/j.issn.1672-6731.2015.01.010. [Study 235] Ma SR, Tong Q, Lin Y, et al. Berberine treats atherosclerosis via a vitamine-like effect down-regulating Choline-TMA-TMAO production pathway in gut microbiota. Signal Transduct Target Ther. 2022;7:207. doi:10.1038/s41392-022-01027-6 [Study 754] Lei L, Wang B, Zhao L, et al; for the BRAVO Collaborative Group. Berberine and adiposity in diabetes-free individuals with obesity and MASLD: a randomized clinical trial. JAMA Netw Open. 2026;9(1):e2554152. doi:10.1001/jamanetworkopen.2025.54152[Study 755] Kong WJ, Wei J, Abidi P, et al. Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins. Nat Med. 2004;10(12):1344-1351. doi:10.1038/nm1135 [Study 757] Zheng J, Wang T, Zhou Y, et al. Berberine ameliorates atherosclerosis by inhibiting the phenotypic transition of vascular smooth muscle cells via suppression of the JAK2/STAT3 signaling pathway. Eur J Pharmacol. 2025;1007:178234. doi:10.1016/j.ejphar.2025.178234[Study 758] Derosa G, D'Angelo A, Bonaventura A, Bianchi L, Romano D, Maffioli P. Effects of berberine on lipid profile in subjects with low cardiovascular risk. Expert Opin Biol Ther. 2013;13(4):475-482. doi:10.1517/14712598.2013.776037[Study 759] Yang L, Zhu W, Zhang X, Zhou X, Wu W, Shen T. Efficacy and safety of berberine for several cardiovascular diseases: a systematic review and meta-analysis of randomized controlled trials. Phytomedicine. 2023;112:154716. doi:10.1016/j.phymed.2023.154716 Please use the following link to submit your critique: https://bit.ly/PhysionicCritiqueDisclaimer: None of the information provided by this brand is a replacement for your physician's advice. This brand is information for the sake of knowledge and the options of choice it provides, not in any way a personalized prescription. Please consult your physician before making any health related changes.
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