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Assisi, Italy 🇮🇹 Assisi is a hill town in central Italy’s Umbria region. It was the birthplace of St. Francis (1181–1226), one of Italy’s patron saints. The Basilica of St. Francis is a massive, 2-level church, consecrated in 1253. Its 13th-century frescoes portraying the life of St. Francis have been attributed to Giotto and Cimabue, among others. The crypt houses the saint’s stone sarcophagus.