Fibrodysplasia Ossificans Progressiva (FOP) is a very rare and mysterious genetic connective tissue disorder.
As stated FOP is a very rare disorder, effecting an estimated 4000 people worldwide.
As a result, it is a disorder that is caused by genetic mutation at birth, occurring sporadically and usually only affecting a single individual within a family.
FOP is characterised by abnormal bone growth throughout the human body.
Causing ligaments, tendons and skeletal muscle, to transform into bone through metamorphosis. This makes movement become extremely difficult as joints start to lock in place.
The most well-known case of this disorder is that of Harry Raymond Eastlack.
Who donated his body to the Mutter Museum in Philadelphia after his death to pneumonia in 1973 for research purposes, were it continues to be researched to this day. Harry was 40 Years old.
Due to this donation there are clear images of the extent to which the skeleton continues to grow throughout the life of a person who is affected by FOP, with many areas of the body being completely submerged in bone.
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