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Epidermodysplasia verruciformis (EV), also known as "Tree man" syndrome, is an exceptionally rare skin condition characterized by painful bark-like growths that extensively cover the body, particularly the extremities. Individuals with weakened immune systems are particularly vulnerable to the distressing disorder. It is most frequently inherited as an autosomal recessive trait. Scientists don’t know the exact number of people who have the condition. About 600 have been reported in medical literature since EV was first identified by researchers in 1922.