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John, please could you review this article from Israel national News, it says the risk of myocarditis following mRNA COVID vaccination is around 133 times greater than the background risk in the population, is this true? If it is true, why is this not all over MSM?https://www.israelnationalnews.com/news/321238Myocarditis Cases Reported After mRNA-Based COVID-19 Vaccination in the US From December 2020 to August 2021 (25 January)https://jamanetwork.com/journals/jama/fullarticle/2788346JAMA. 2022;327(4):331-340. doi:10.1001/jama.2021.24110ImportanceVaccination against COVID-19 provides clear public health benefits, but vaccination also carries potential risks. The risks and outcomes of myocarditis after COVID-19 vaccination are unclear.To describe reports of myocarditis and the reporting rates after mRNA-based COVID-19 vaccination in the US.Descriptive studyReports of myocarditis to the Vaccine Adverse Event Reporting System (VAERS)https://www.cdc.gov/vaccinesafety/ensuringsafety/monitoring/vaers/index.htmlAfter mRNA-based COVID-19 vaccine administrationBetween December 2020 and August 2021 in n = 192,405,448 older than 12 years of age in the USDuring the analytic periodBNT162b2 vaccine, 12 years and oldermRNA-1273 vaccine, 18 years and overExposuresVaccination with BNT162b2 (Pfizer-BioNTech) or mRNA-1273 (Moderna)Main Outcomes and MeasuresExpected rates of myocarditis by age and sex were calculated using 2017-2019 claims data. For persons younger than 30 years of age, medical record reviews and clinician interviews were conducted to describe clinical presentation, diagnostic test results, treatment, and early outcomes.Results Among 192,405,448 personsReceiving a total of 354,100, 845 mRNA vaccines1,991 reports of myocarditis to VAERS1,626 met the case definition of myocarditisOf those with myocarditisMedian age, 21 years (IQR, 16-31 years)Median time to symptom onset, 2 days (IQR, 1-3 days)MalesComprised 82% of myocarditis casesReporting rates for cases of myocarditisWithin 7 days after COVID-19 vaccination,exceeded the expected rates of myocarditis across multiple age and sex strata Rates of myocarditis were highest after the second vaccination doseAdolescent males aged 12 to 15 years70.7 per million doses of the BNT162b2 vaccine(One case per 14,144 vaccinations)Males aged 16 to 17 years105.9 per million doses of the BNT162b2 vaccine(One case per 9,442 vaccinations)Males aged 18 to 24 years52.4 per million doses of the BNT162b2 vaccine(One case per 19,083 vaccinations)56.3 per million doses of the mRNA-1273 vaccine(One case per 17,761 vaccinations)Myocarditis in the under 30s826 cases of myocarditis, who had detailed clinical information availableOf these 826 cases of myocarditis792 of 809 (98%) had elevated troponin levels569 of 794 (72%) had abnormal electrocardiogram results223 of 312 (72%) had abnormal cardiac magnetic resonance imaging resultsHospital data784 of 813 (96%) were hospitalized577 of 661 (87%) had resolution of presenting symptoms by hospital dischargeMost common treatmentNonsteroidal anti-inflammatory drugs 589 of 676 (87%). 7.26 + 105.86 = 113.12Expected, 1.34113.12 = 84.41.34Supplementhttps://cdn.jamanetwork.com/ama/content_public/journal/jama/938849/joi210145supp1_prod_1643643679.10447.pdf?Expires=1647637972&Signature=fDd-WcjZGOHWosWN6O3PYFJ50-QtvggoNqARMaCBDPD65PY90fgxv3Zgb7r5GEJXDkEDw3Rwf8w2ChfqekovqSPCQs7BfbdV5PvwT2SmKWShsOtS0-1WdgXnaXVuzZ8NsHY8lRWdTvCTjmtQRMDMu9I7fa-9Psm7maerrGZ~yHgsGJtIt8DbtngF4siXisrF1mNTYK1HDTFbMT-veAWAdauW-HSyiNKZXX34MDNdEIb~U~VE2RXxO68HsP7Su8~5B52aOU1XsK8ftzL00LvhEdn~Y~Tr46UQvofPLSCo2BrnH4edqS8j1PfR3XfTEa~fkJitRFlS3sbKbUB4mmiFuw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGACDC’s case definition of probable myocarditis
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