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"Be Careful With Your Fragrance Choice Did you know that the fragrance from perfumes and colognes can cause anything from respiratory issues to hyperpigmentation? If you've ever gotten a headache when their rich aroma reaches your nostrils, there's a good reason why. Some perfumes are really hazardous! When sprayed directly onto the skin, they are absorbed into the bloodstream, delivering chemicals throughout the body. The very attractive bottles in which perfumes are sold disguise their toxic nature."