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🩺 Get your personalized health plan: https://drstanfield.com✔️ X: https://x.com/BradStanfieldMD✔️ Patreon: https://www.patreon.com/bradstanfieldmdHere are the links to the research papers referenced in the video:Verve-102 adverse eventshttps://www.cgtlive.com/view/verve-moves-on-second-gen-cardiovascular-crispr-therapy-verve-102-adverse-eventsFramingham Heart Study — abouthttps://www.framinghamheartstudy.org/fhs-about/Optimal LDL 50–70 mg/dLhttps://pubmed.ncbi.nlm.nih.gov/15172426/LDL causes ASCVD (EAS consensus)https://academic.oup.com/eurheartj/article/38/32/2459/3745109Broken PCSK9 protects against CHDhttps://www.nejm.org/doi/full/10.1056/NEJMoa054013Lower LDL extends lifespan (MR)https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bcp.14811CRISPR-Cas9 discovery historyhttps://pmc.ncbi.nlm.nih.gov/articles/PMC9377665/CRISPR acquired resistance (2007)https://embryo.asu.edu/pages/crispr-acquired-resistance-against-viruses-2007CRISPR is bacterial immunityhttps://www.science.org/doi/10.1126/science.1138140Programmable Cas9 DNA cleavagehttps://www.science.org/doi/10.1126/science.12258292020 Nobel Chemistry for CRISPRhttps://pmc.ncbi.nlm.nih.gov/articles/PMC7782372/CRISPR causes large deletionshttps://pmc.ncbi.nlm.nih.gov/articles/PMC6390938/SCID-X1 gene therapy leukemiahttps://www.jci.org/articles/view/35700David Liu — Broad biohttps://www.broadinstitute.org/bios/david-liuDavid Liu profile — Harvard Magazinehttps://www.harvardmagazine.com/science/david-liu-harvard-gene-editing-research-disease-curesVERVE-102 Heart-2 trial (NEJM)https://www.nejm.org/doi/full/10.1056/NEJMoa2601283Intellia MAGNITUDE clinical holdhttps://ir.intelliatx.com/news-releases/news-release-details/intellia-therapeutics-provides-update-magnitude-clinical-trialsIntellia nex-z patient deathhttps://www.cgtlive.com/view/patient-treated-trial-intellia-transthyretin-amyloidosis-gene-editing-therapy-nex-z-diesLiu Breakthrough Prize / Tapley — Harvard Gazettehttps://news.harvard.edu/gazette/story/2025/04/rewriting-genetic-destiny-gene-base-editing/Base-edited CAR7 T-cells in T-ALL (NEJM)https://www.nejm.org/doi/full/10.1056/NEJMoa2505478PCSK9 base editing in primates (Nature)https://www.nature.com/articles/s41586-021-03534-yLilly VERVE-102 resultshttps://investor.lilly.com/news-releases/news-release-details/single-dose-lillys-pcsk9-base-editor-verve-102-reduced-pcsk9-88Thumbnail by James KellyVideo edited by Troy YoungScript by John MillikenThe content contained in this video, and its accompanying description, is not intended to replace viewers’ relationships with their own medical practitioner. Always speak with your doctor regarding the content of this channel, and especially before using any products, services, or devices discussed on this channel.
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